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Marvel's Spider-Man set symbol

Marvel's Spider-Man Combos

Marvel's Spider-Man (2025) made 720 two- and three-card Commander combos possible: combos whose newest card was first printed in Marvel's Spider-Man. The most-played two-card combo is Anti-Venom, Horrifying Healer + With Great Power . . . (prevent all damage that would be dealt to you). Spider-Man, Peter Parker appears in more of them than any other Marvel's Spider-Man card (102).

Browse the full Marvel's Spider-Man card list

Combo data from Commander Spellbook. Longer 4+ card lines are left out on purpose.

720
Combos
32
Two-card
688
Three-card
209
New cards in set

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Top combo cards in Marvel's Spider-Man

  1. 102
  2. 85
  3. 61
  4. 56
  5. 53
  6. 49
  7. 36
  8. 34

Older cards that got better

  1. 45
  2. 33
  3. 33
  4. 33
  5. 29
  6. 25
  7. 21
  8. 21

New commanders that combo

  1. 102
  2. 85
  3. 53
  4. 34
  5. 33
  6. 32
  7. 18
  8. 13

Most-played Marvel's Spider-Man combos

  1. Anti-Venom, Horrifying Healer + With Great Power . . . Prevent all damage that would be dealt to you · Lock 2-card · Spicy · How it works
  2. Anti-Venom, Horrifying Healer + Pariah Lock · Prevent all damage that would be dealt to you 2-card · Spicy · How it works
  3. Anti-Venom, Horrifying Healer + Pariah's Shield Prevent all damage that would be dealt to you · Lock 2-card · Spicy · How it works
  4. Anti-Venom, Horrifying Healer + Gideon's Sacrifice Prevent all damage that would be dealt to you · Lock 2-card · Spicy · How it works
  5. Gwenom, Remorseless + Sensei's Divining Top + Aetherflux Reservoir Near-infinite damage · Infinite card draw 3-card · Exhibition · How it works
  6. With Great Power . . . + Stuffy Doll Draw the game 2-card · Spicy · How it works
  7. Gwenom, Remorseless + Sensei's Divining Top + Sheoldred, the Apocalypse Infinite card draw · Near-infinite lifegain 3-card · Exhibition · How it works
  8. Chameleon, Master of Disguise + Felidar Guardian Infinite creature LTB · Infinite creature ETB 2-card · Exhibition · How it works
  9. With Great Power . . . + Caduceus, Staff of Hermes Prevent all damage that would be dealt to you · Lock 2-card · Spicy · How it works
  10. Lyla, Holographic Assistant + Fathom Mage Infinite card draw · Infinite draw triggers 2-card · Ruthless · How it works
  11. Mister Negative + Wall of Blood + Phyrexian Unlife Near-infinite lifeloss for target opponent · Target opponent loses the game 3-card · Spicy · How it works
  12. Peter Parker's Camera + Brago, King Eternal Infinite artifact ETB · Infinite artifact LTB 2-card · Exhibition · How it works
  13. Strength of Will + Hardened Scales + Walking Ballista Infinite damage · Infinite +1/+1 counters on a creature 3-card · Exhibition · How it works
  14. Mister Negative + Wall of Blood + Platinum Angel Near-infinite lifeloss for target opponent · Target opponent loses the game 3-card · Spicy · How it works
  15. Mister Negative + Wall of Blood + Pact Weapon Near-infinite lifeloss for target opponent · Target opponent loses the game 3-card · Spicy · How it works
  16. Lyla, Holographic Assistant + Benthic Biomancer Infinite card draw · Infinite draw triggers 2-card · Ruthless · How it works
  17. Gwenom, Remorseless + Mortuary + Death Cultist Infinite creature LTB · Infinite creature ETB 3-card · Exhibition · How it works
  18. Strength of Will + Kami of Whispered Hopes + Walking Ballista Infinite damage · Infinite +1/+1 counters on a creature 3-card · Exhibition · How it works
  19. Vibrant Cityscape + Tifa Lockhart + Scale Up Target opponent loses the game 3-card · Exhibition · How it works
  20. J. Jonah Jameson + Aggravated Assault Infinite artifact ETB · Infinite artifact LTB 2-card · Spicy · How it works
Castable in Cards
Result
Bracket

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